Friday, March 9, 2012

The Above Shows the compounds which are used in Cardiac Therapy and Some are Anti hypertensives.  48 compounds taken from drug bank. The association of the drugs are being done based on the (SLAP), a highly developed powerful tool for drug target prediction . The compounds are being scored based on the semantic association of   1863 targets . After prunning 1500 targets are being set. But further prunning is required to remove unneccessary targets for these compounds. Below is the distribution of compounds with respect to targets quite a big plot . 
The idea is to find most associated proteins for the Cardiac therapy drugs and Anti hypersensitives. Are these compounds Prosmiscuos Or show polypharmacoogy ? some compounds are natural compounds here and these compounds get easily associated with many proteins.