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Showing posts with label tuberculosis. Show all posts
Showing posts with label tuberculosis. Show all posts

Sunday, January 11, 2015

Tuberculosis and the Global Clinical Study Map using Clinical Trials data from Web .

People around the world through blogs , newsletters and other forms of media showing how deadly diseases like TB are spreading and killing people. Between last 2-3 years lot of people have come up with ideas like open source development in drugs , lot of consortium have been formed to move with the research. With a bit of data mining on the clinical trial data we can easily see whats going on with the drug discovery arena . Using some r libraries we can easily access the clinical trial data from clinicaltrail.gov website and parse the xml files . I searched for "tuberculosis" with the start date and 1/1/2013 and end date 12/31/2014 and the trials with a "closed" status including all the age groups. After looking at this map I would ask the Indian Health ministry, Is India waiting for the west to develop its drugs or it does want the people to die of this lethal disease ? Only 3 clinical trails are being done but none of them are Phase I-IV trails for new drugs. Is the scientific community just abandon their hands on this ? In USA two medical centers(Lincoln and cleveland) already seem to be working on the new drugs, one is bedaquiline (NCT02216331) and other SQ109(NCT01874314). I didn't look on European centers and Africa. The code for this available @ git . I used rMaps library with Leaflet.js library. One can play with any disease and with different start and end date and with trial status. The Map below (2013-14) is iframe embedded on html which is done using the command using rMaps package -

map$show('iframesrc',cdn=TRUE)

I found some issues with with the geocode function from the ggmap package takes a lot of time to access the google api for latitude and longitude . If anyone has a faster way to get those let me know.

The first maps shows the clinical trials from 2009-2014 which designates a lot of Trials being done on TB in India . But from 2013-14 no further interest was made on TB .    


Map from 2013 -14